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KMID : 0882419930450030322
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Korean Journal of Medicine
1993 Volume.45 No. 3 p.322 ~ p.327
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Prevalene of Anti-HC in Healthy Subjects in Ulsan Area
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정지인
손석호/조욱현/정정희/김용림/이진관
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Abstract
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ackground : The prevalence of antibody to hepatitis C virus (anti-HCV) in healthy subjects from Korean has been investigated in various studies. But most of these studies were estimated from data in blood donors who were mostly young adults. So
these
studies could not represent the prevalence of anti-HCV age groups and its age distribution.
Method : The prevalence of anti-HCV among healthy subjects in Ulsan area was
evaluated using commercially available enzme immunoassay. We studied a correlation between
anti-HCV and alanine aminotransferase (ALT) level, and between anti-HCV and HBsAg.
Effects of increasing age and blood transfusion were also evaluated.
Results :
1) The overall prevalence of anti-HCV was 1.07% among 3,000 healty subjects.
2) Male to female ratio was 2.5:1. The prevalence of anti-HCV among male subjects
(1.21%) was higher than that among female subjects (0.7%).
3) Anti-HCV prevalence increased with increasing age through the fourth decade of life.
4) There was no significant difference both in the prevalence of anti-HCV in healthy
subjects with or without HBsAg and in the prevalence of anti-HCV in healthy subjects with
or without the history of transfusion.
5) Anti-HCV prevalence increased linearly with the increase of alanine aminotransferase
level.
Conclusion : The prevalence of anti-HCV in healthy subjects in Ulsan area was 1.07%.
There was a significant increas with increasing age above 30 years. There was a good
correlation between the prevalence of anti-HCV and ALT level, but the prevalence of
anti-HCV was not associated with blood transfusion.
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KEYWORD
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